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INTRODUCTION Lennox-Gastaut Syndrome (LGS) was initially outlined from the results of studies into the encephalopathy (brain function/disorder) of `petit-mal' seizures by Lennox and Davis (1950), and was later expanded to its now widely accepted form as a syndrome by Gastaut, Roger, Soulayrol, Tassinari, Regis, Dravet, Bernard, Pinscard, and Saint-Jean (1966). LGS is described as having three interrelated symptoms, consisting of the following: 1. Epileptic seizures (axial tonic, atypical absences, atonic seizures, and less frequently - myoclonias, generalised tonic-clonic, and partial seizures). 2. Electroencephalogram (EEG) abnormalities. (slow spike-wave in the awake EEG, and rapid burst rhythms during sleep). 3. Slowing in mental development with personality disorders. LGS describes one of the most severe forms of childhood epilepsies. An extensive review of the literature suggests that LGS usually develops between the ages of 1 and 8 years, affects more males than females, with half having no known cause and the remainder having various aetiologys (causing factors) affecting the brain and directly causing epilepsy. This article examines the clinical manifestations of the LGS, detailing the seizure