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Hamlet's Disease The somber images of poison and disease taint the pages of Hamlet, and shadow the corruption pervading the recent and future events of the castle. The poison with which Claudius kills King Hamlet spreads in a sense throughout the country, until "something is rotten in Denmark", as Marcellus notes (I.4.90). Shakespeare shades in words of sickness continually during the play, perhaps serving best to illustrate the ill condition of affairs plaguing not only Denmark, but the characters as well. Shakespeare immediately conveys the sense of cold and apathy in the opening scene. As the play opens in the cool, black night, Barnardo and Francisco are high atop the looming walls of Elsinore, keeping watch for the impending revenge of enemy Fortinbras (I.1). Midnight strikes and Barnardo notes, subtly referring to the sentiment of Denmark, that "tis bitter cold, and I am sick at heart" (I.1.8). Since the beloved King Hamlet has died and the Queen remarried, the morale of the people is low, and cold. The act continues, and the Ghost appears out of the dark shadows (I.1). Horatio, who had doubted the men's earlier details of sightings, now contemplates the reasons for the Ghost's visit as the spirit disappears into the