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Cigarette smoking is one of the major killers in the world. The biggest side affect from smoking is Cancer. Cancer is a group of many related diseases. All forms of Cancer involve out-of-control growth and spread of abnormal cells. The American Cancer Society estimates that cigarettes are responsible for about 419,000 deaths in the united states each year. The largest killing cancer is Lung Cancer, which accounts for 30% of all U.S cancer deaths. The risk of dying from lung cancer is 22 times higher for males, and 12 times higher for female smokers as oppose to nonsmokers. Additionally, smokers are at an increased risk for cancer of the larynx, oral cavity , esophagus, bladder, kidney and pancreas. Health effects of smoking Smoking causes a five time increase in the risk of dying from chronic bronchitis and emphysema, and a two time increase in deaths from diseases of the heart and coronary arteries. Smoking also increases the risk of stroke by 40-50% in men and 60% in women. Researchers have also proven that mothers who smoke while pregnant or before they got pregnant usually give birth to babies with birth defects, who are premature or are underweight. This is probably because of a decrease in blood flow to the placenta.