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The Journal of Biology article “Differences in the way mammalian cells and yeast cells coordinate cell growth and cell-cycle progression” by Ian Conlon and Martin Ruff can be interpreted as the classic comparison of plants cells and animals cells between the way that they grow and replicate. The type of animals cells chosen to experiment on was the rat Schwann cells and for the plant, yeast cells. Within the article, it was concluded that the Schwann cells and the yeast cells use different mechanisms to coordinate their growth with cell-cycle progression. The yeast cells use cell-check points in the G1 and/or G2 phases where the cell pauses and adjusts until the cell is adequate to move on to the S Phase or M Phase. Yet, the animal cells apparently use extracellular signals to coordinate their growth with cell-cycle progression, which is not elaborated on. Beside