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Pet Variables Nuclear Medicine, along with medicine in general, is always changing. The current revolution taking place in nuclear medicine is among the most exciting. The development of whole-body Positron Emission Tomography (PET), together with the imaging agent F18 FDG (flurodeoxyglucose) enables the accurate non-invasive detection and staging of cancer. PET was developed in the late 1960’s, but recent developments have resulted in its recognition as an invaluable clinical test for tumor imaging. PET and nuclear medicine are unique and different than other imaging modalities because they do not have the unique ability to image functional processes, such as tumor metabolic activity, in vivo. The basic principles of PET are based on the detection of photons