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Using a gram stain to detect bacteria Norcardia crassostreae in the hemolymph of Pacific oyster Crassostrae gigas. Aquaculture or the farming of aquatic organisms is a method to relive the fishing pressure on wild stocks and may offer tremendous socio-economic benefits to both developing and wealthy countries. Many countries are finding the farming of aquatic organisms such as shellfish to be an effective and beneficial alternative means to increase abundance of catch. The practice of aquaculture has suffered in many countries due to disease among the shellfish, which can kill up to 80% of the harvest (Wooten et al.2003 ),(Rodriguez et. al.200) and spread sickness to people eating infected shellfish. The sustainability of shrimp culture is questionable as pathological problems in the majority of shrimp producing countries is increasing (Bachere 2000). An understanding of the physiology